Founded at the Abramson Cancer Center at the University of Pennsylvania

Text Messaging and Take-At-Home Tests Boost Colorectal Cancer Screening

Take-At-Home Colorectal Cancer Screening

By providing the opportunity for early discovery and curative treatment, regular screenings have been shown to reduce mortality rates for colorectal cancer (CRC). Unfortunately, regular screening rates are low across the United States, and in particular, participation in these screenings occurs at much lower rates amongst those who are uninsured, low income, and/or members of racial and ethnic minority groups. While the colonoscopy is the gold standard for CRC detection, the fecal immunochemical test (FIT), a take-at-home test, has been shown to increase screening participation. Particularly when circumstances such as the COVID-19 pandemic make it difficult for patients to come into the hospital, the benefits of an FIT test are even more compelling.

This study examined whether sending take-at-home FIT kits directly to patients’ homes would increase screening rates at a Federally Qualified Health Center (FQHC) in Philadelphia, which serves a population composed largely of racial and ethnic minority groups, Medicaid beneficiaries, and uninsured patients. Patients in the intervention arm of this randomized control trial received an alert via text message that an FIT kit would be coming in the mail, at which point they could opt out of receiving the kit. Non-responders received a kit in the mail as well as information highlighting the benefits of screening. Participants in the control arm did not receive a kit but rather a reminder text to contact the clinic to discuss screening. Of the 440 participants, 87.7% were Black, 19.1% were uninsured, and 49.6% were primarily Medicaid beneficiaries. The CRC screening rate was 17.3 percentage points higher in the intervention arm at 19.6% compared to the screening rate of 2.3% in the control arm.

Mail-home kits have many benefits particularly for under-resourced community health centers. They reduce clinician time and reach individuals who may not otherwise come to the clinic. Furthermore, the cost is very low, only $0.75 per participant. Most importantly, the at-home tests improve screening rates substantially beyond simple reminders. The study also demonstrates how text messaging and insights from behavioral science might boost uptake. Noting the relatively low overall participation rates, future studies could look into factors that might affect participation, such as low literacy or housing instability.

Sarah W. Huf, MBBS, PhD; David A. Asch, MD, MBA; Kevin G. Volpp, MD, PhD; Catherine Reitz, MPH; Shivan J. Mehta, MD, MBA, MSHP

The Family Practice & Counseling Network/Health Annex

National Cancer Institute; Commonwealth Fund

Health Equity
Behavior Changes Incentives

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