Alix Seif

Associate Professor, Pediatrics, Perelman School of Medicine

Alix Seif, MD, MPH, is an Innovation Faculty member at the Penn Center for Cancer Care Innovation (PC3I), an attending physician in Cellular Therapy & Transplantation and Hematologic Malignancies at the Children’s Hospital of Philadelphia (CHOP), and an Associate Professor of Pediatrics at the Perelman School of Medicine. She is a past holder of the Richard and Sheila Sanford Endowed Chair in Pediatric Oncology.

Dr. Seif’s research focuses on advancing patient-centered care for children, adolescents, and young adults with leukemia, developing and implementing interventions that improve clinical outcomes, quality of life, and equity. She created the evidence-based AML Care at Home toolkit, which personalizes the care setting for patients receiving chemotherapy for acute myeloid leukemia, and will lead a national trial to implement this intervention.

As Director of Clinical Research for CHOP’s Center for Childhood Cancer Research and member of the CHOP Institutional Review Board, she partners with patients and caregivers to improve the clinical research consent process. She chairs the Children’s Oncology Group’s Patient-centered Informed Consent Improvement Working Group, which aims to 1) empower patients and caregivers to make informed decisions about participation in clinical research; 2) establish standardized best practices for informed consent; and 3) increase research participation of historically marginalized groups to improve representation and generalizability.

Dr. Seif received her medical education at the Oregon Health Sciences University before completing her residency in Pediatrics and a Pediatric Hematology-Oncology fellowship, both at CHOP. She received a Master of Public Health in Epidemiology and Biostatistics from Oregon Health Sciences University and a Master of Arts in Linguistics from McGill University.