Tessa Cook

Vice Chair of Practice Transformation, Perelman School of Medicine

Tessa Cook, MD, PhD is an Innovation Faculty member at the Penn Center for Cancer Care Innovation (PC3I) and Associate Professor and the Vice Chair of Practice Transformation in the Department of Radiology at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia. She completed her doctoral work in quantitative image processing in the Penn Image Computing and Science Laboratory (PICSL). During her residency, Dr. Cook developed RADIANCE, only the second open-source radiation exposure monitoring tool used worldwide in 2010. She is an active member of multiple radiology societies, including the ACR, SIIM, AAR, and RSNA. She received one of the 2011 E. Stephen Amis, Jr. Fellowships in Quality and Safety from the ACR. She was one of the four AAR GERRAF fellows for 2013-2015.

In 2020, Dr. Cook was inducted into the College of SIIM Fellows and received the inaugural Dr. Ruth Dayhoff Award for the Advancement of Women in Medical Imaging Informatics. She is the past Chair of SIIM. She became a Fellow of the AAR as well as of the ACR in 2025. Dr. Cook currently enjoys an academic appointment in radiology that combines her clinical work in cardiovascular imaging with her research and innovation interests in imaging informatics. She is the director of the Imaging Informatics Fellowship in the Department of Radiology, as well as the clinical director of the 3-D and Advanced Imaging Laboratory. In her various roles, she is pursuing innovative engineering and imaging informatics approaches to enhance the delivery of patient care in radiology and improve radiologists’ workflow.