Founded at the Abramson Cancer Center at the University of Pennsylvania
Matthew Press

Matthew Press, MD, MSc

Physician Executive, Penn Primary Care

Medical Director, Primary Care Service Line

Matthew Press, MD, MSc is the Physician Executive of Penn Medicine Primary Care and the Medical Director of the Penn Medicine Primary Care Service Line. In these roles, he helps lead practice transformation and population health management across a network of 80 primary care practices in the University of Pennsylvania Health System. He is also Interim Chair of the Department of Family Medicine and Community Health in the Perelman School of Medicine at Penn and an Associate Professor in the Department of Medicine. He practices general internal medicine and is engaged in research in the areas of population health and payment reform.


Prior to his current position, Dr. Press was a member of the senior leadership team at the Center for Medicare and Medicaid Innovation at CMS, where he helped develop and implement several new payment and care delivery models including ACOs, bundled payments, integrated mental health, and medical homes, as well as the Health Care Payment Learning and Action Network, a national public-private partnership dedicated to health care payment reform. His work has been published in the New England Journal of Medicine, JAMA, and Health Affairs, and has been covered by The New York Times and the Associated Press. He received his MD from Brown University and completed his residency and the RWJF Clinical Scholars Program at the University of Pennsylvania. Dr. Press served on PC3I’s Governing Board until 2020.

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