An American Cancer Society Clinician Scientist Development Grant (CSDG) has been awarded to PC3I Faculty Allison Barz Leahy, MD, MSCE. The CSDG provides five years of funding support to junior faculty trained primarily as clinicians who want to maintain clinical practice and conduct cancer research.
Dr. Barz Leahy’s work centers on the use of patient-reported outcome (PRO) measures for symptom monitoring in pediatric cancer patients, with a focus in chimeric antigen receptor (CAR) T cell therapy, a type of treatment in which a patient’s own T cells are altered to attack cancer cells. Through this funding, she will develop novel early warning systems that leverage PROs to inform meaningful and actionable clinical outcomes in pediatric CAR T cell therapy.
In other populations, PROs have been used for toxicity monitoring and have done so more effectively than traditional laboratory measures, but haven’t been assessed to the same extent in pediatric oncology populations. In this pioneering study, PROs collected from pediatric oncology patients and their caregivers will be combined with traditional clinical data to develop advanced predictive models to identify patients most at risk for bad outcomes, such as life-threatening side effects, the premature loss of CAR T cells, or relapse following treatment. These models will allow clinicians to anticipate and mitigate catastrophic events in a particularly high-risk population and improve outcomes overall for children with cancer.
PC3I Faculty Oluwadamilola "Lola" Fayanju Leading Innovative Collaborative Research Initiative with Gilead Sciences
PC3I Associate Director Lola Fayanju is leading a collaborative research initiative with Gilead Sciences to optimize collection of SBDoH from patients with breast cancer.
Bekelman Named to National Cancer Policy Forum
PC3I Director Justin Bekelman was recently named a member of the National Cancer Policy Forum.
Cancer Service Line & PC3I Select 2023 Innovation Accelerator Project
PC3I and the Cancer Service Line (CSL) have announced the 2023 Innovation Accelerator project. The project team, led by Heather Sheaffer, DSW, LCSW, FACHE, will focus on developing a solution to make non-clinical resources widely available and accessible to patients.